Keto Versus Mediterranean Weight loss plan: Which Is Finest for T2 Diabetics and Prediabetics?

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Impact of a Ketogenic Weight loss plan versus a Mediterranean Weight loss plan on HbA1c in People with Prediabetes and Sort 2 Diabetes Mellitus: the Interventional Keto-Med Randomized Crossover Trial

Proper off the bat, I do not like that they studied each diabetes and prediabetics. There have been solely 40 unique research individuals, with full information on solely 33. Why lump the 2 collectively?

Contributors adopted every weight-reduction plan for 12 weeks then lab information and physique weight had been assessed.

The researchers conclusions:

HbA1c [a measure of blood sugar control] was not totally different between weight-reduction plan phases after 12-weeks, however improved from baseline on each diets, seemingly resulting from a number of shared dietary facets. WFKD [ketogenic diet] was useful for better lower in triglycerides, but additionally had potential untoward dangers from elevated LDL-C, and decrease nutrient intakes from avoiding legumes, fruits, and entire intact grains, in addition to being much less sustainable.

Triglycerides dropped extra on the keto weight-reduction plan, no shock. Physique weight dropped the identical for each diets, 7-8%. HDL-cholesterol (the “good ldl cholesterol”) rose 11% on keto and seven% on the Mediterranean weight-reduction plan. HgbA1c dropped the identical on each diets, about 8% from baseline. Each diets result in consuming ~300 energy much less per day than baseline consumption.

Dr Bret Scher addressed the elevated LDL-cholesterol (aka “dangerous ldl cholesterol”) over at

The authors reported that LDL “dangerously” rose 10% on the keto weight-reduction plan. However was it actually a harmful change? Triglycerides went down on the keto weight-reduction plan, as we’d anticipate. And as we noticed in 2018 with the Virta Well being trial, on common, LDL went up 10%. Nonetheless, the calculated cardiac danger rating went down 12%.

By way of answering the headline query, Keto Versus Mediterranean Weight loss plan: Which Is Finest for T2 Diabetics and Prediabetics?, the reply actually is determined by long-term information regarding longevity and numerous ailments. This research would not reply the query.

What say you?

Steve Parker, MD

front cover of Conquer Diabetes and Prediabetes